RNA Sequencing in Cancer

This cluster involves research utilizing RNA sequencing to understand gene expression changes and epigenetic modifications associated with various cancers. It highlights the role of exosomes and other genetic exchanges in tumor biology.

RNA sequencing
gene expression
epigenetics
mRNA
microRNA
exosomes

35,331 papers

Parent topic: Cancer Research and Treatment

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Papers Over Time

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Top Papers

Mapping And Quantifying Mammalian Transcriptomes By RNA-Seq

2008 · 11,518 citations

Exosome-mediated Transfer Of mRNAs And microRNAs Is A Novel Mechanism Of Genetic Exchange Between Cells

2007 · 10,755 citations

DNA Methylation Patterns And Epigenetic Memory

2002 · 5,993 citations

Summaries Of Affymetrix GeneChip Probe Level Data

2003 · 4,274 citations

Human microRNA Genes Are Frequently Located At Fragile Sites And Genomic Regions Involved In Cancers

2004 · 3,656 citations

Minfi: A Flexible And Comprehensive Bioconductor Package For The Analysis Of Infinium DNA Methylation Microarrays

2014 · 3,419 citations

Comprehensive Analysis Of mRNA Methylation Reveals Enrichment In 3′ UTRs And Near Stop Codons

2012 · 3,387 citations

LMO2 -Associated Clonal T Cell Proliferation In Two Patients After Gene Therapy For SCID-X1

2003 · 3,236 citations

The Impact Of microRNAs On Protein Output

2008 · 3,216 citations

Reference-based Analysis Of Lung Single-Cell Sequencing Reveals A Transitional Profibrotic Macrophage

2019 · 3,088 citations

The Transcriptional Landscape Of The Mammalian Genome

2005 · 3,087 citations

Analysis Of The Human Tissue-specific Expression By Genome-wide Integration Of Transcriptomics And Antibody-based Proteomics

2014 · 2,991 citations

Telomere Measurement By Quantitative PCR

2002 · 2,986 citations

Many Human Large Intergenic Noncoding RNAs Associate With Chromatin-Modifying Complexes And Affect Gene Expression

2009 · 2,582 citations

circRNA Biogenesis Competes With Pre-mRNA Splicing

2014 · 2,509 citations

Switching From Repression To Activation: MicroRNAs Can Up-Regulate Translation

2007 · 2,395 citations

The Landscape Of Long Noncoding RNAs In The Human Transcriptome

2015 · 2,334 citations

An Atlas Of Active Enhancers Across Human Cell Types And Tissues

2014 · 2,291 citations

Many Roads To Maturity: microRNA Biogenesis Pathways And Their Regulation

2009 · 2,280 citations

The Answer Is 17 Years, What Is The Question: Understanding Time Lags In Translational Research

2011 · 2,221 citations