Regulation of Immune Cells in Tumor

Research in this cluster explores the interactions between immune cell subsets and tumor cells, focusing on regulatory mechanisms and immune evasion. It highlights the roles of myeloid-derived suppressor cells, T cells, and checkpoints in cancer.

myeloid cells
T lymphocytes
tumor microenvironment
immune evasion
PD-1

65,099 papers

Parent topic: Infectious Disease and Immunology

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Papers Over Time

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Top Papers

Myeloid-derived Suppressor Cells As Regulators Of The Immune System

2009 · 5,751 citations

Two Subsets Of Memory T Lymphocytes With Distinct Homing Potentials And Effector Functions

1999 · 5,152 citations

PD-1 And Its Ligands In Tolerance And Immunity

2008 · 4,532 citations

Surface Markers On Human T And B Lymphocytes

1972 · 3,601 citations

Generation Of Large Numbers Of Dendritic Cells From Mouse Bone Marrow Cultures Supplemented With Granulocyte/Macrophage Colony-Stimulating Factor.

1992 · 3,549 citations

A Gene Encoding An Antigen Recognized By Cytolytic T Lymphocytes On A Human Melanoma

1991 · 3,455 citations

A Progress Report On The Treatment Of 157 Patients With Advanced Cancer Using Lymphokine-Activated Killer Cells And Interleukin-2 Or High-Dose Interleukin-2 Alone

1987 · 3,438 citations

‘Actively Acquired Tolerance’ Of Foreign Cells

1953 · 3,369 citations

Enhancement Of Antitumor Immunity By CTLA-4 Blockade

1996 · 3,337 citations

Innate And Adaptive Immune Cells In The Tumor Microenvironment

2013 · 3,268 citations

Functions Of Natural Killer Cells

2008 · 3,139 citations

Lymphoproliferation Disorder In Mice Explained By Defects In Fas Antigen That Mediates Apoptosis

1992 · 3,114 citations

Chimeric Antigen Receptor–Modified T Cells In Chronic Lymphoid Leukemia

2011 · 3,089 citations

Chimeric Antigen Receptor–Modified T Cells For Acute Lymphoid Leukemia

2013 · 3,034 citations

Observations On The Systemic Administration Of Autologous Lymphokine-Activated Killer Cells And Recombinant Interleukin-2 To Patients With Metastatic Cancer

1985 · 3,033 citations

Naturally Arising CD4+ Regulatory T Cells For Immunologic Self-Tolerance And Negative Control Of Immune Responses

2004 · 3,004 citations

Vaccination With Irradiated Tumor Cells Engineered To Secrete Murine Granulocyte-Macrophage Colony-Stimulating Factor Stimulates Potent, Specific, And Long-Lasting Anti-Tumor Immunity.

1993 · 3,004 citations

Lymphokine-activated Killer Cell Phenomenon. Lysis Of Natural Killer-Resistant Fresh Solid Tumor Cells By Interleukin 2-Activated Autologous Human Peripheral Blood Lymphocytes.

1982 · 2,815 citations

Differentiation Of Effector CD4 T Cell Populations

2010 · 2,797 citations

Tolerogenic Dendritic Cells

2003 · 2,754 citations