Osteoclast Biology and Function

This cluster focuses on the biological mechanisms underlying osteoclast differentiation and activation, important for bone remodeling and pathologies such as osteoporosis and osteosarcoma. Research explores the predictive value of different assays on bone bioactivity and their implications in clinical outcomes.

osteoclast
bone remodeling
osteosarcoma
bioactivity
fracture healing
bone diseases

167,746 papers

Parent topic: Oral and Skeletal Health Research

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Papers Over Time

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Top Papers

How Useful Is SBF In Predicting In Vivo Bone Bioactivity?

2006 · 7,813 citations

Pathologic Fracture In Osteosarcoma: Association With Poorer Overall Survival

2016 · 5,673 citations

Osteoclast Differentiation And Activation

2003 · 5,547 citations

Bone: Formation By Autoinduction

1965 · 5,272 citations

Bone Histomorphometry: Standardization Of Nomenclature, Symbols, And Units: Report Of The Asbmr Histomorphometry Nomenclature Committee

2009 · 5,066 citations

Novel Regulators Of Bone Formation: Molecular Clones And Activities

1988 · 3,865 citations

Guidelines For Assessment Of Bone Microstructure In Rodents Using Micro-Computed Tomography

2010 · 3,672 citations

Osf2/Cbfa1: A Transcriptional Activator Of Osteoblast Differentiation

1997 · 3,426 citations

Targeted Disruption Of Cbfa1 Results In A Complete Lack Of Bone Formation Owing To Maturational Arrest Of Osteoblasts.

1997 · 3,400 citations

Targeted Disruption Of Results In A Complete Lack Of Bone Formation Owing To Maturational Arrest Of Osteoblasts

1997 · 3,399 citations

Bone Resorption By Osteoclasts

2000 · 3,393 citations

Osf2/Cbfa1: A Transcriptional Activator Of Osteoblast Differentiation.

1997 · 3,362 citations

Remodelling The Extracellular Matrix In Development And Disease

2014 · 3,338 citations

The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required For Osteoblast Differentiation And Bone Formation.

2002 · 2,903 citations

Metastasis To Bone: Causes, Consequences And Therapeutic Opportunities

2002 · 2,477 citations

Cbfa1, A Candidate Gene For Cleidocranial Dysplasia Syndrome, Is Essential For Osteoblast Differentiation And Bone Development

1997 · 2,287 citations

Pamidronate (Aredia) And Zoledronate (Zometa) Induced Avascular Necrosis Of The Jaws: A Growing Epidemic

2003 · 2,276 citations

Cbfa1, A Candidate Gene For Cleidocranial Dysplasia Syndrome, Is Essential For Osteoblast Differentiation And Bone Development.

1997 · 2,253 citations

THE MATERIAL BONE: Structure-Mechanical Function Relations

1998 · 2,245 citations

Standardized Nomenclature, Symbols, And Units For Bone Histomorphometry: A 2012 Update Of The Report Of The ASBMR Histomorphometry Nomenclature Committee

2012 · 2,180 citations