Oncology Clinical Guidelines

This cluster synthesizes guidelines and trial results for the clinical management of various cancers. It plays a critical role in informing best practices and improving patient care.

clinical guidelines
cancer treatment
trial results
management strategies
best practices
protocol development

245,597 papers

Parent topic: Cancer Research and Treatment

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Papers Over Time

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Top Papers

The European Organization For Research And Treatment Of Cancer QLQ-C30: A Quality-of-Life Instrument For Use In International Clinical Trials In Oncology

1993 · 12,902 citations

2015 American Thyroid Association Management Guidelines For Adult Patients With Thyroid Nodules And Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force On Thyroid Nodules And Differentiated Thyroid Cancer

2016 · 11,317 citations

Safety And Activity Of Anti–PD-L1 Antibody In Patients With Advanced Cancer

2012 · 6,851 citations

FOLFIRINOX Versus Gemcitabine For Metastatic Pancreatic Cancer

2011 · 6,409 citations

The American Joint Committee On Cancer: The 7Th Edition Of The AJCC Cancer Staging Manual And The Future Of TNM

2010 · 6,304 citations

Revised American Thyroid Association Management Guidelines For Patients With Thyroid Nodules And Differentiated Thyroid Cancer

2009 · 6,042 citations

Improvements In Survival And Clinical Benefit With Gemcitabine As First-Line Therapy For Patients With Advanced Pancreas Cancer: A Randomized Trial.

1997 · 5,456 citations

The Eighth Edition AJCC Cancer Staging Manual: Continuing To Build A Bridge From A Population-Based To A More “Personalized” Approach To Cancer Staging

2017 · 4,804 citations

Atezolizumab Plus Bevacizumab In Unresectable Hepatocellular Carcinoma

2020 · 4,769 citations

Trastuzumab In Combination With Chemotherapy Versus Chemotherapy Alone For Treatment Of HER2-positive Advanced Gastric Or Gastro-Oesophageal Junction Cancer (ToGA): A Phase 3, Open-Label, Randomised Controlled Trial.

2010 · 4,747 citations

Cetuximab Monotherapy And Cetuximab Plus Irinotecan In Irinotecan-Refractory Metastatic Colorectal Cancer

2004 · 4,666 citations

Radiotherapy Plus Cetuximab For Squamous-Cell Carcinoma Of The Head And Neck

2006 · 4,654 citations

Efficacy And Safety Of Sorafenib In Patients In The Asia-Pacific Region With Advanced Hepatocellular Carcinoma: A Phase III Randomised, Double-Blind, Placebo-Controlled Trial.

2008 · 4,602 citations

Final Version Of 2009 AJCC Melanoma Staging And Classification

2009 · 4,071 citations

Trastuzumab In Combination With Chemotherapy Versus Chemotherapy Alone For Treatment Of HER2-positive Advanced Gastric Or Gastro-Oesophageal Junction Cancer (ToGA): A Phase 3, Open-Label, Randomised Controlled Trial

2010 · 3,737 citations

Cisplatin Plus Gemcitabine Versus Gemcitabine For Biliary Tract Cancer

2010 · 3,581 citations

AJCC Cancer Staging Manual

2002 · 3,575 citations

Nivolumab Plus Ipilimumab Versus Sunitinib In Advanced Renal-Cell Carcinoma

2018 · 3,564 citations

Modified RECIST (mRECIST) Assessment For Hepatocellular Carcinoma

2010 · 3,500 citations

Lenvatinib Versus Sorafenib In First-Line Treatment Of Patients With Unresectable Hepatocellular Carcinoma: A Randomised Phase 3 Non-Inferiority Trial

2018 · 3,456 citations