Molecular Biology of Breast Cancer

This cluster centers on the molecular and genetic profiling of breast cancer. It emphasizes correlations between genetic alterations and clinical outcomes, impacting treatment decisions and prognosis.

breast cancer
molecular profiling
HER2
tumor biology
survival rates
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202,807 papers

Parent topic: Cancer Research and Treatment

AI-assisted content · The overview, paper groupings, and influence analysis on this page are AI-generated. They are intended as a starting point for exploring the field and may contain inaccuracies. Report an error

Papers Over Time

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Top Papers

Molecular Portraits Of Human Breast Tumours

2000 · 13,231 citations

Human Breast Cancer: Correlation Of Relapse And Survival With Amplification Of The HER-2/ Neu Oncogene

1987 · 11,587 citations

Comprehensive Molecular Portraits Of Human Breast Tumours

2012 · 10,528 citations

Gene Expression Patterns Of Breast Carcinomas Distinguish Tumor Subclasses With Clinical Implications

2001 · 9,362 citations

Prospective Identification Of Tumorigenic Breast Cancer Cells

2003 · 8,985 citations

Gene Expression Profiling Predicts Clinical Outcome Of Breast Cancer

2002 · 8,211 citations

Studies Of The HER-2/ Neu Proto-Oncogene In Human Breast And Ovarian Cancer

1989 · 7,226 citations

A Strong Candidate For The Breast And Ovarian Cancer Susceptibility Gene BRCA1

1994 · 5,979 citations

Effects Of Chemotherapy And Hormonal Therapy For Early Breast Cancer On Recurrence And 15-Year Survival: An Overview Of The Randomised Trials.

2005 · 5,958 citations

Effects Of Chemotherapy And Hormonal Therapy For Early Breast Cancer On Recurrence And 15-Year Survival: An Overview Of The Randomised Trials

2005 · 5,822 citations

A Gene-Expression Signature As A Predictor Of Survival In Breast Cancer

2002 · 5,554 citations

Pathological Prognostic Factors In Breast Cancer. I. The Value Of Histological Grade In Breast Cancer: Experience From A Large Study With Long-Term Follow-Up

1991 · 5,402 citations

A Multigene Assay To Predict Recurrence Of Tamoxifen-Treated, Node-Negative Breast Cancer

2004 · 5,377 citations

Twenty-Year Follow-up Of A Randomized Trial Comparing Total Mastectomy, Lumpectomy, And Lumpectomy Plus Irradiation For The Treatment Of Invasive Breast Cancer

2002 · 5,328 citations

Tamoxifen For Prevention Of Breast Cancer: Report Of The National Surgical Adjuvant Breast And Bowel Project P-1 Study

1998 · 5,200 citations

The Genomic And Transcriptomic Architecture Of 2,000 Breast Tumours Reveals Novel Subgroups

2012 · 4,853 citations

Trastuzumab Plus Adjuvant Chemotherapy For Operable HER2-Positive Breast Cancer

2005 · 4,819 citations

Trastuzumab After Adjuvant Chemotherapy In HER2-Positive Breast Cancer

2005 · 4,565 citations

Repeated Observation Of Breast Tumor Subtypes In Independent Gene Expression Data Sets

2003 · 4,478 citations

Identification Of Human Triple-Negative Breast Cancer Subtypes And Preclinical Models For Selection Of Targeted Therapies

2011 · 4,330 citations