Mechanisms of Proteolytic Enzymes

This cluster investigates the actions and mechanisms of proteolytic enzymes, particularly their role in protein structure processing and signal peptide identification. Emphasis is placed on the biochemical pathways involved in protein assembly and enzyme activity.

proteolytic enzymes
protein cleavage
signal peptides
gel electrophoresis
biochemical mechanisms

103,413 papers

Parent topic: Biochemical Methods and Enzymology

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Papers Over Time

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Top Papers

Cleavage Of Structural Proteins During The Assembly Of The Head Of Bacteriophage T4

1970 · 283,543 citations

Identification Of Prokaryotic And Eukaryotic Signal Peptides And Prediction Of Their Cleavage Sites

1997 · 5,145 citations

Peptide Mapping By Limited Proteolysis In Sodium Dodecyl Sulfate And Analysis By Gel Electrophoresis.

1977 · 4,952 citations

On The Size Of The Active Site In Proteases. I. Papain.

1967 · 4,588 citations

Measurement Of Cellulase Activities

1987 · 4,300 citations

Disk Electrophoresis Of Basic Proteins And Peptides On Polyacrylamide Gels

1962 · 4,053 citations

Peptide Mapping By Limited Proteolysis In Sodium Dodecyl Sulfate And Analysis By Gel Electrophoresis.

1977 · 3,987 citations

On The Size Of The Active Site In Proteases. I. Papain

1967 · 3,977 citations

β-Secretase Cleavage Of Alzheimer's Amyloid Precursor Protein By The Transmembrane Aspartic Protease BACE

1999 · 3,620 citations

[17] Amylases, Α And Β

1955 · 3,190 citations

Crystalline Soybean Trypsin Inhibitor

1947 · 3,139 citations

Molecular Cloning Of A Functional Thrombin Receptor Reveals A Novel Proteolytic Mechanism Of Receptor Activation.

1991 · 2,746 citations

Amino Acid Sequences Common To Rapidly Degraded Proteins: The PEST Hypothesis

1986 · 2,666 citations

Cleavage Of poly(ADP-ribose) Polymerase By A Proteinase With Properties Like ICE

1994 · 2,644 citations

The Preparation And Enzymatic Hydrolysis Of Reduced And S-carboxymethylated Proteins.

1963 · 2,601 citations

The Preparation And Properties Of Two New Chromogenic Substrates Of Trypsin.

1961 · 2,528 citations

Protein Inhibitors Of Proteinases

1980 · 2,494 citations

Human Plasma Proteinase Inhibitors

1983 · 2,379 citations

Molecular Cloning Of A Functional Thrombin Receptor Reveals A Novel Proteolytic Mechanism Of Receptor Activation

1991 · 2,309 citations

The Preparation And Enzymatic Hydrolysis Of Reduced And S-Carboxymethylated Proteins

1963 · 2,039 citations