Matrix Metalloproteinases Role in Cancer

This research focuses on the functions of matrix metalloproteinases in cancer biology, delving into their role in tumor progression and the tumor microenvironment. Studies highlight their regulatory mechanisms and implications for cancer therapies.

matrix metalloproteinases
cancer progression
tumor microenvironment
biomarkers
tumor biology

39,166 papers

Parent topic: Integrated Surgical and Health Studies

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Papers Over Time

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Top Papers

New Functions For The Matrix Metalloproteinases In Cancer Progression

2002 · 5,365 citations

Matrix Metalloproteinases: Regulators Of The Tumor Microenvironment

2010 · 4,175 citations

Matrix Metalloproteinases

1999 · 4,076 citations

Matrix Metalloproteinases And Tissue Inhibitors Of Metalloproteinases

2003 · 3,945 citations

How Matrix Metalloproteinases Regulate Cell Behavior

2001 · 3,421 citations

A Metalloproteinase Disintegrin That Releases Tumour-Necrosis Factor-Α From Cells

1997 · 2,967 citations

Matrix Metalloproteinases: A Review

1993 · 2,888 citations

Structure And Function Of Matrix Metalloproteinases And TIMPs

2006 · 2,738 citations

A Novel Heterodimeric Cysteine Protease Is Required For Interleukin-1Βprocessing In Monocytes

1992 · 2,614 citations

A Matrix Metalloproteinase Expressed On The Surface Of Invasive Tumour Cells

1994 · 2,608 citations

Matrix Metalloproteinase Inhibitors And Cancer—Trials And Tribulations

2002 · 2,515 citations

Matrix Metalloproteinase-9 Triggers The Angiogenic Switch During Carcinogenesis

2000 · 2,501 citations

Matrix Metalloproteinases And The Regulation Of Tissue Remodelling

2007 · 2,474 citations

Matrix Metalloproteinases And Their Inhibitors In Connective Tissue Remodeling

1991 · 2,347 citations

Increased Expression Of Matrix Metalloproteinases And Matrix Degrading Activity In Vulnerable Regions Of Human Atherosclerotic Plaques.

1994 · 2,329 citations

Proteoglycans: Structures And Interactions

1991 · 2,003 citations

Collagens—structure, Function, And Biosynthesis

2003 · 1,993 citations

Use Of A Mixture Of Proteinase-Free Collagenases For The Specific Assay Of Radioactive Collagen In The Presence Of Other Proteins

1971 · 1,785 citations

Extracellular Matrix Degradation And Remodeling In Development And Disease

2011 · 1,742 citations

Matrix Metalloproteinases And Tumor Metastasis

2006 · 1,696 citations