Innovative DNA Sequencing Technologies

This cluster investigates advanced methodologies in DNA sequencing, focusing on improved algorithms for processing and analyzing large genomic datasets. Techniques include filtering strategies and normalization of sequencing data.

DNA sequencing
data processing
filtering algorithms
normalization
big data

2,885 papers

Parent topic: Genomic Data Analysis Techniques

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Papers Over Time

19901995200020052010201520202025

Top Papers

An Improved Filtering Algorithm For Big Read Datasets

2016 · 865 citations

Preprocessing, Normalization And Integration Of The Illumina HumanMethylationEPIC Array With Minfi

2016 · 648 citations

Highly Parallel SNP Genotyping

2003 · 539 citations

Population Dynamics Of Normal Human Blood Inferred From Somatic Mutations

2018 · 487 citations

Detection Of DNA Base Modifications By Deep Recurrent Neural Network On Oxford Nanopore Sequencing Data

2019 · 243 citations

The Single-Cell Sequencing: New Developments And Medical Applications

2019 · 234 citations

DeepSignal: Detecting DNA Methylation State From Nanopore Sequencing Reads Using Deep-Learning

2019 · 178 citations

Deepbinner: Demultiplexing Barcoded Oxford Nanopore Reads With Deep Convolutional Neural Networks

2018 · 175 citations

Improving Cell Mixture Deconvolution By Identifying Optimal DNA Methylation Libraries (IDOL)

2016 · 158 citations

Index Switching Causes “Spreading-Of-Signal” Among Multiplexed Samples In Illumina HiSeq 4000 DNA Sequencing

2017 · 150 citations

RCP: A Novel Probe Design Bias Correction Method For Illumina Methylation BeadChip

2016 · 120 citations

Hepatitis Disease Diagnosis Using A Novel Hybrid Method Based On Support Vector Machine And Simulated Annealing (SVM-SA)

2012 · 117 citations

A Novel SNPs Detection Method Based On Gold Magnetic Nanoparticles Array And Single Base Extension

2012 · 113 citations

Hardware Acceleration Of BWA-MEM Genomic Short Read Mapping For Longer Read Lengths

2018 · 106 citations

A Label-Free Strategy For SNP Detection With High Fidelity And Sensitivity Based On Ligation-Rolling Circle Amplification And Intercalating Of Methylene Blue

2009 · 101 citations

Systematic Benchmarking Of Tools For CpG Methylation Detection From Nanopore Sequencing

2021 · 99 citations

Intracellular Entropy‐Driven Multi‐Bit DNA Computing For Tumor Progression Discrimination

2020 · 93 citations

A Novel Automated Assay With Dual-Color Hybridization For Single-Nucleotide Polymorphisms Genotyping On Gold Magnetic Nanoparticle Array

2010 · 87 citations

Discrimination Indices As Screening Tests For Β-Thalassemic Trait

2007 · 87 citations

Unsupervised Technique For Robust Target Separation And Analysis Of DNA Microarray Spots Through Adaptive Pixel Clustering

2002 · 82 citations