Innate Immunity and Cytokine Response

This cluster focuses on the innate immune responses to pathogens, emphasizing cytokine signaling and the role of immune cell types in defense mechanisms. It supports understanding of disease pathogenesis.

innate immunity
cytokines
immune response
pathogen recognition
host defense

348,080 papers

Parent topic: Infectious Disease and Immunology

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Papers Over Time

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Top Papers

Pathogen Recognition And Innate Immunity

2006 · 9,808 citations

TH1 And TH2 Cells: Different Patterns Of Lymphokine Secretion Lead To Different Functional Properties

1989 · 7,899 citations

Adhesion Receptors Of The Immune System

1990 · 7,671 citations

Exploring The Full Spectrum Of Macrophage Activation

2008 · 7,493 citations

The Role Of Pattern-Recognition Receptors In Innate Immunity: Update On Toll-like Receptors

2010 · 7,379 citations

COVID-19: Consider Cytokine Storm Syndromes And Immunosuppression

2020 · 7,040 citations

Innate Immune Recognition

2002 · 6,720 citations

Immunochemical Quantitation Of Antigens By Single Radial Immunodiffusion

1965 · 6,450 citations

Two Types Of Murine Helper T Cell Clone. I. Definition According To Profiles Of Lymphokine Activities And Secreted Proteins.

1986 · 5,933 citations

A Rapid Method For The Isolation Of Functional Thymus-Derived Murine Lymphocytes

1973 · 5,867 citations

Acute-Phase Proteins And Other Systemic Responses To Inflammation

1999 · 5,576 citations

The Chemokine System In Diverse Forms Of Macrophage Activation And Polarization

2004 · 5,301 citations

Alternative Activation Of Macrophages

2003 · 5,193 citations

Macrophage Plasticity And Polarization: In Vivo Veritas

2012 · 5,001 citations

Toll-Like Receptors

2003 · 4,976 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators Of Immune Responses

1998 · 4,952 citations

Efficient Presentation Of Soluble Antigen By Cultured Human Dendritic Cells Is Maintained By Granulocyte/Macrophage Colony-Stimulating Factor Plus Interleukin 4 And Downregulated By Tumor Necrosis Factor Alpha.

1994 · 4,919 citations

Function And Activation Of NF-kappaB In The Immune System

1994 · 4,914 citations

Macrophage Activation And Polarization: Nomenclature And Experimental Guidelines

2014 · 4,782 citations

A Human Homologue Of The Drosophila Toll Protein Signals Activation Of Adaptive Immunity

1997 · 4,761 citations