In Vivo Gene Therapy Studies

This area focuses on the applications of gene therapy in vivo, investigating techniques and methodologies for successful treatment in neurological disorders. It emphasizes animal models and experimental protocols.

gene therapy
in vivo
neurological disorders
research protocols
animal models

47,260 papers

Parent topic: Neuroscience and Neurological Disorders

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Papers Over Time

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Top Papers

Cerebral Organoids Model Human Brain Development And Microcephaly

2013 · 4,200 citations

A Simple Practice Guide For Dose Conversion Between Animals And Human

2016 · 4,051 citations

Animal Research: Reporting In Vivo Experiments: The ARRIVE Guidelines

2010 · 3,236 citations

Direct Gene Transfer Into Mouse Muscle In Vivo

1990 · 2,987 citations

Non-viral Vectors For Gene-Based Therapy

2014 · 2,666 citations

Gene Therapy Of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

2000 · 2,377 citations

In Vivo Protein Transduction: Delivery Of A Biologically Active Protein Into The Mouse

1999 · 2,307 citations

Progress And Problems With The Use Of Viral Vectors For Gene Therapy

2003 · 2,203 citations

Advanced Mammalian Gene Transfer: High Titre Retroviral Vectors With Multiple Drug Selection Markers And A Complementary Helper-Free Packaging Cell Line

1990 · 2,190 citations

Nonviral Vectors For Gene Delivery

2008 · 2,178 citations

Transplantation Of Embryonic Dopamine Neurons For Severe Parkinson's Disease

2001 · 2,142 citations

Single-Dose Gene-Replacement Therapy For Spinal Muscular Atrophy

2017 · 1,825 citations

Germline Transmission And Tissue-Specific Expression Of Transgenes Delivered By Lentiviral Vectors

2002 · 1,803 citations

In Vivo Gene Transfer With Retroviral Vector-Producer Cells For Treatment Of Experimental Brain Tumors

1992 · 1,787 citations

Nutrition Of Animal Cells In Tissue Culture. I. Initial Studies On A Synthetic Medium.,

1950 · 1,733 citations

Mice Devoid Of PrP Are Resistant To Scrapie.

1993 · 1,719 citations

Hydrodynamics-based Transfection In Animals By Systemic Administration Of Plasmid DNA

1999 · 1,593 citations

Effects Of Varying The Vehicle For OsO4 In Tissue Fixation

1957 · 1,586 citations

Reporting Animal Research: Explanation And Elaboration For The ARRIVE Guidelines 2.0

2020 · 1,429 citations

Novel Adeno-Associated Viruses From Rhesus Monkeys As Vectors For Human Gene Therapy

2002 · 1,362 citations