Hypertension and Endothelial Dynamics

This cluster investigates the mechanisms of hypertension and the critical role of endothelial cells in vascular function and blood pressure regulation. Research includes various vasoconstrictor peptides and their effects on smooth muscle relaxation.

hypertension
endothelial cells
vasoconstriction
blood pressure
smooth muscle
vascular health
cardiovascular

207,386 papers

Parent topic: Kidney Health and Disease

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Papers Over Time

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Top Papers

The Seventh Report Of The Joint National Committee On Prevention, Detection, Evaluation, And Treatment Of High Blood Pressure<SUBTITLE>The JNC 7 Report</SUBTITLE>

2003 · 17,186 citations

A Novel Potent Vasoconstrictor Peptide Produced By Vascular Endothelial Cells

1988 · 12,890 citations

The Obligatory Role Of Endothelial Cells In The Relaxation Of Arterial Smooth Muscle By Acetylcholine

1980 · 12,816 citations

Seventh Report Of The Joint National Committee On Prevention, Detection, Evaluation, And Treatment Of High Blood Pressure

2003 · 11,299 citations

Telmisartan Plus HCTZ Vs. Amlodipine Plus HCTZ In Older Patients With Systolic Hypertension: Results From A Large Ambulatory Blood Pressure Monitoring Study

2002 · 8,198 citations

Age-specific Relevance Of Usual Blood Pressure To Vascular Mortality: A Meta-Analysis Of Individual Data For One Million Adults In 61 Prospective Studies.

2002 · 7,859 citations

2014 Evidence-Based Guideline For The Management Of High Blood Pressure In Adults

2014 · 6,719 citations

Global Burden Of Hypertension: Analysis Of Worldwide Data.

2005 · 5,358 citations

Angiotensin-converting Enzyme 2 Is A Functional Receptor For The SARS Coronavirus

2003 · 5,228 citations

A Randomized Trial Of Intensive Versus Standard Blood-Pressure Control

2015 · 5,045 citations

The Sixth Report Of The Joint National Committee On Prevention, Detection, Evaluation, And Treatment Of High Blood Pressure

1997 · 4,927 citations

Endothelium-derived Relaxing Factor Produced And Released From Artery And Vein Is Nitric Oxide.

1987 · 4,907 citations

Effects Of Intensive Blood-Pressure Lowering And Low-Dose Aspirin In Patients With Hypertension: Principal Results Of The Hypertension Optimal Treatment (HOT) Randomised Trial. HOT Study Group.

1998 · 4,756 citations

Tissue Distribution Of ACE2 Protein, The Functional Receptor For SARS Coronavirus. A First Step In Understanding SARS Pathogenesis

2004 · 4,755 citations

2007 Guidelines For The Management Of Arterial Hypertension

2007 · 4,639 citations

Effects On Blood Pressure Of Reduced Dietary Sodium And The Dietary Approaches To Stop Hypertension (DASH) Diet

2001 · 4,544 citations

2013 ESH/ESC Guidelines For The Management Of Arterial Hypertension

2013 · 4,278 citations

2013 ESH/ESC Guidelines For The Management Of Arterial Hypertension

2013 · 4,054 citations

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline For The Prevention, Detection, Evaluation, And Management Of High Blood Pressure In Adults

2018 · 3,849 citations

Application Of A Radioimmunoassay For Angiotensin I To The Physiologic Measurements Of Plasma Renin Activity In Normal Human Subjects1

1969 · 3,723 citations