Genome Engineering with CRISPR

This cluster focuses on the applications of CRISPR technology for genome engineering. It covers advancements in gene editing techniques that have broad implications for genetic research and therapy.

CRISPR
gene editing
genome engineering
genetic therapies
molecular biology

63,229 papers

Parent topic: Genomic and Proteomic Research

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Papers Over Time

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Top Papers

Genome Engineering Using The CRISPR-Cas9 System

2013 · 9,631 citations

Identification Of The Cystic Fibrosis Gene: Cloning And Characterization Of Complementary DNA

1989 · 7,450 citations

The New Frontier Of Genome Engineering With CRISPR-Cas9

2014 · 5,285 citations

Development And Applications Of CRISPR-Cas9 For Genome Engineering

2014 · 4,693 citations

Improved Vectors And Genome-Wide Libraries For CRISPR Screening

2014 · 4,454 citations

Genetic Regulatory Mechanisms In The Synthesis Of Proteins.

1961 · 4,409 citations

The Zebrafish Reference Genome Sequence And Its Relationship To The Human Genome

2013 · 4,008 citations

Systematic Functional Analysis Of The Caenorhabditis Elegans Genome Using RNAi

2003 · 3,251 citations

Separation Of Yeast Chromosome-Sized DNAs By Pulsed Field Gradient Gel Electrophoresis.

1984 · 2,367 citations

A Positive Selection For Mutants Lacking Orotidine-5′-Phosphate Decarboxylase Activity In Yeast: 5-Fluoro-Orotic Acid Resistance

1984 · 2,291 citations

Isolation And Characterization Of Rat And Human Glyceraldehyde-3-Phosphate Dehydrogenase cDNAs: Genomic Complexity And Molecular Evolution Of The Gene

1985 · 2,212 citations

Genes And Salt Tolerance: Bringing Them Together

2005 · 2,186 citations

Electroblotting Of Multiple Gels: A Simple Apparatus Without Buffer Tank For Rapid Transfer Of Proteins From Polycrylamide To Nitrocellulose

1984 · 2,130 citations

cDNA Sequence Of Human Apolipoprotein(A) Is Homologous To Plasminogen

1987 · 2,088 citations

Isolation And Characterization Of A Zinc Finger Polypeptide Gene At The Human Chromosome 11 Wilms' Tumor Locus.

1990 · 1,730 citations

Yeast Vectors For The Controlled Expression Of Heterologous Proteins In Different Genetic Backgrounds

1995 · 1,716 citations

Blue Silver: A Very Sensitive Colloidal Coomassie G-250 Staining For Proteome Analysis

2004 · 1,646 citations

Isogenic Strain Construction And Gene Mapping In Candida Albicans.

1993 · 1,596 citations

Protein Arginine Methylation In Mammals: Who, What, And Why

2009 · 1,524 citations

Rat Insulin Genes: Construction Of Plasmids Containing The Coding Sequences

1977 · 1,502 citations