Chemical Mutagens Studies

This area examines the impact of chemical mutagens on DNA and their role in carcinogenesis. Research includes methodologies for detecting mutagenicity and understanding underlying biochemical mechanisms.

mutagenesis
carcinogenesis
chemical toxicity
DNA damage
biochemical mechanisms

197,526 papers

Parent topic: Pharmacology and Toxicology

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Papers Over Time

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Top Papers

Methods For Detecting Carcinogens And Mutagens With The Salmonella/mammalian-microsome Mutagenicity Test.

1975 · 5,612 citations

Revised Methods For The Salmonella Mutagenicity Test.

1983 · 5,180 citations

Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement

2009 · 3,618 citations

Detection Of Carcinogens As Mutagens In The Salmonella/microsome Test: Assay Of 300 Chemicals.

1975 · 2,911 citations

Investigation Of The Alamar Blue (Resazurin) Fluorescent Dye For The Assessment Of Mammalian Cell Cytotoxicity

2000 · 2,784 citations

Ecotoxicology Of Human Pharmaceuticals

2006 · 2,519 citations

Interindividual Variations In Human Liver Cytochrome P-450 Enzymes Involved In The Oxidation Of Drugs, Carcinogens And Toxic Chemicals: Studies With Liver Microsomes Of 30 Japanese And 30 Caucasians.

1994 · 2,270 citations

Perfluoroalkyl Acids: A Review Of Monitoring And Toxicological Findings

2007 · 2,182 citations

A Review Of Human carcinogens—Part B: Biological Agents

2009 · 2,160 citations

Carcinogens Are Mutagens: A Simple Test System Combining Liver Homogenates For Activation And Bacteria For Detection

1973 · 2,104 citations

Translocation Of Inhaled Ultrafine Particles To The Brain

2004 · 2,062 citations

Lipid Extraction Of Tissues With A Low-Toxicity Solvent

1978 · 1,902 citations

Trimmed Spearman-Karber Method For Estimating Median Lethal Concentrations In Toxicity Bioassays

1977 · 1,866 citations

ProTox-II: A Webserver For The Prediction Of Toxicity Of Chemicals

2018 · 1,851 citations

The In Vitro Micronucleus Technique

2000 · 1,843 citations

In Vitro Toxicity Of Nanoparticles In BRL 3A Rat Liver Cells

2005 · 1,776 citations

Organoselenium And Organotellurium Compounds: Toxicology And Pharmacology

2004 · 1,695 citations

Concordance Of The Toxicity Of Pharmaceuticals In Humans And In Animals

2000 · 1,648 citations

The Micronucleus Test.

1975 · 1,592 citations

Mechanisms Of Membrane Toxicity Of Hydrocarbons

1995 · 1,551 citations