Bone Health and Osteoclast Research

This research cluster focuses on the biological mechanisms regulating bone health, particularly the roles of various cytokines and proteins in osteoclast differentiation and function. Key studies explore the relationships between osteoprotegerin, RANKL, and bone density.

osteoclasts
osteoprotegerin
bone density
cytokines
RANKL
bone health
osteoporosis

129,847 papers

Parent topic: Kidney Health and Disease

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Papers Over Time

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Top Papers

Osteoprotegerin Ligand Is A Cytokine That Regulates Osteoclast Differentiation And Activation.

1998 · 4,487 citations

Osteoprotegerin: A Novel Secreted Protein Involved In The Regulation Of Bone Density.

1997 · 4,299 citations

Osteoclast Differentiation Factor Is A Ligand For Osteoprotegerin/Osteoclastogenesis-Inhibitory Factor And Is Identical To TRANCE/RANKL

1998 · 3,819 citations

An Estimate Of The Worldwide Prevalence And Disability Associated With Osteoporotic Fractures

2006 · 3,647 citations

Osteoporosis Prevention, Diagnosis, And Therapy

2001 · 3,501 citations

Incidence And Economic Burden Of Osteoporosis-Related Fractures In The United States, 2005-2025

2006 · 3,366 citations

Risk Factors For Hip Fracture In White Women

1995 · 3,319 citations

The Diagnosis Of Osteoporosis

2009 · 3,309 citations

Randomised Trial Of Effect Of Alendronate On Risk Of Fracture In Women With Existing Vertebral Fractures. Fracture Intervention Trial Research Group.

1996 · 3,224 citations

Meta-analysis Of How Well Measures Of Bone Mineral Density Predict Occurrence Of Osteoporotic Fractures

1996 · 3,215 citations

Reduction Of Vertebral Fracture Risk In Postmenopausal Women With Osteoporosis Treated With Raloxifene<SUBTITLE>Results From A 3-Year Randomized Clinical Trial</SUBTITLE>

1999 · 3,137 citations

Osteoprotegerin Ligand Is A Cytokine That Regulates Osteoclast Differentiation And Activation

1998 · 3,002 citations

Vitamin D3and Calcium To Prevent Hip Fractures In Elderly Women

1992 · 2,887 citations

Denosumab For Prevention Of Fractures In Postmenopausal Women With Osteoporosis

2009 · 2,848 citations

Hip Fractures In The Elderly: A World-Wide Projection

1992 · 2,640 citations

Clinician’s Guide To Prevention And Treatment Of Osteoporosis

2014 · 2,547 citations

Epidemiology And Outcomes Of Osteoporotic Fractures.

2002 · 2,536 citations

Involutional Osteoporosis

1986 · 2,414 citations

Assessment Of Fracture Risk And Its Application To Screening For Postmenopausal Osteoporosis. Report Of A WHO Study Group.

1994 · 2,293 citations

Effects Of Risedronate Treatment On Vertebral And Nonvertebral Fractures In Women With Postmenopausal Osteoporosis<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>

1999 · 2,289 citations