Bioinformatics for Sequence Studies

This cluster is dedicated to bioinformatics tools and methods for sequence analysis. It aims to merge computational approaches with biological data to facilitate genomic research.

bioinformatics
sequence analysis
computational tools
genomic data
alignment methods

113,401 papers

Parent topic: Genomic and Proteomic Research

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Papers Over Time

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Top Papers

Gapped BLAST And PSI-BLAST: A New Generation Of Protein Database Search Programs

1997 · 63,970 citations

CLUSTAL W: Improving The Sensitivity Of Progressive Multiple Sequence Alignment Through Sequence Weighting, Position-Specific Gap Penalties And Weight Matrix Choice

1994 · 57,261 citations

The Sequence Alignment/Map Format And SAMtools

2009 · 50,763 citations

Fast Gapped-Read Alignment With Bowtie 2

2012 · 44,434 citations

Fast And Accurate Short Read Alignment With Burrows-Wheeler Transform

2009 · 41,034 citations

The Neighbor-Joining Method: A New Method For Reconstructing Phylogenetic Trees.

1987 · 40,198 citations

Gene Ontology: Tool For The Unification Of Biology

2000 · 34,547 citations

KEGG: Kyoto Encyclopedia Of Genes And Genomes

2000 · 27,782 citations

Cutadapt Removes Adapter Sequences From High-Throughput Sequencing Reads

2011 · 23,133 citations

The SILVA Ribosomal RNA Gene Database Project: Improved Data Processing And Web-Based Tools

2012 · 23,081 citations

The Genome Analysis Toolkit: A MapReduce Framework For Analyzing Next-Generation DNA Sequencing Data

2010 · 22,461 citations

BEDTools: A Flexible Suite Of Utilities For Comparing Genomic Features

2010 · 22,311 citations

SPAdes: A New Genome Assembly Algorithm And Its Applications To Single-Cell Sequencing

2012 · 20,635 citations

featureCounts: An Efficient General Purpose Program For Assigning Sequence Reads To Genomic Features

2013 · 19,506 citations

Full-length Transcriptome Assembly From RNA-Seq Data Without A Reference Genome

2011 · 17,317 citations

Geneious Basic: An Integrated And Extendable Desktop Software Platform For The Organization And Analysis Of Sequence Data

2012 · 16,115 citations

A Rapid Alkaline Extraction Procedure For Screening Recombinant Plasmid DNA

1979 · 15,096 citations

DnaSP V5: A Software For Comprehensive Analysis Of DNA Polymorphism Data

2009 · 13,264 citations

MAFFT: A Novel Method For Rapid Multiple Sequence Alignment Based On Fast Fourier Transform

2002 · 13,200 citations

Multiplex Genome Engineering Using CRISPR/Cas Systems

2013 · 13,052 citations