Adipose Tissue Physiology and Metabolism

Research in this cluster examines the biological functions of adipose tissue as an endocrine organ and its metabolic processes. Key studies focus on hormones secreted by fat cells and their role in metabolic health.

adipose tissue
metabolism
endocrine functions
adiponectin
insulin resistance

79,459 papers

Parent topic: Nutrition and Metabolic Health

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Papers Over Time

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Top Papers

The Fat-Derived Hormone Adiponectin Reverses Insulin Resistance Associated With Both Lipoatrophy And Obesity

2001 · 4,314 citations

Adipose Tissue As An Endocrine Organ

2004 · 4,021 citations

A PGC1-α-dependent Myokine That Drives Brown-Fat-Like Development Of White Fat And Thermogenesis

2012 · 3,824 citations

SREBPs: Activators Of The Complete Program Of Cholesterol And Fatty Acid Synthesis In The Liver

2002 · 3,723 citations

Adiponectin Stimulates Glucose Utilization And Fatty-Acid Oxidation By Activating AMP-activated Protein Kinase

2002 · 3,639 citations

Adipokines In Inflammation And Metabolic Disease

2011 · 3,514 citations

Regulation Of Skeletal Muscle Mass In Mice By A New TGF-p Superfamily Member

1997 · 3,481 citations

XBP1 mRNA Is Induced By ATF6 And Spliced By IRE1 In Response To ER Stress To Produce A Highly Active Transcription Factor.

2001 · 3,268 citations

A Cold-Inducible Coactivator Of Nuclear Receptors Linked To Adaptive Thermogenesis.

1998 · 3,214 citations

Metabolism Of Isolated Fat Cells

1964 · 3,178 citations

SREBPs: Activators Of The Complete Program Of Cholesterol And Fatty Acid Synthesis In The Liver.

2002 · 3,094 citations

Stimulation Of Adipogenesis In Fibroblasts By PPAR Gamma 2, A Lipid-Activated Transcription Factor.

1994 · 3,092 citations

Identification And Expression Cloning Of A Leptin Receptor, OB-R.

1995 · 3,063 citations

The SREBP Pathway: Regulation Of Cholesterol Metabolism By Proteolysis Of A Membrane-Bound Transcription Factor.

1997 · 3,020 citations

The Human Endothelin Family: Three Structurally And Pharmacologically Distinct Isopeptides Predicted By Three Separate Genes.

1989 · 3,016 citations

Cold-Activated Brown Adipose Tissue In Healthy Men

2009 · 2,984 citations

The SREBP Pathway: Regulation Of Cholesterol Metabolism By Proteolysis Of A Membrane-Bound Transcription Factor

1997 · 2,852 citations

A Novel Serum Protein Similar To C1q, Produced Exclusively In Adipocytes

1995 · 2,827 citations

Cloning Of Adiponectin Receptors That Mediate Antidiabetic Metabolic Effects

2003 · 2,777 citations

Stimulation Of Adipogenesis In Fibroblasts By PPARγ2, A Lipid-Activated Transcription Factor

1994 · 2,756 citations